contents:
1. clearance
2. volume of distribution
3. half-life
4. how drugs are cleared by the liver
5. bioavailabiliti and first-pass clearance
6. predecting drugs interactions and the effects of disease states for metabolised drugs
7. clearance of drugs by the kidneys
8. drug protein binding
9. non-linear pharmacokinetics
10. pharmacodynamics-the concentration-effect relationchip
11. designing dose regimens
12. therapeutic drug monitoring.